The Electron Capture 163Holmium experiment ECHo aims to investigate the electron neutrino mass in the sub-eV range by means of the analysis of the calorimetrically measured energy spectrum following the electron capture process of 163Ho. A high precision and high statistics spectrum will be measured by means of low temperature magnetic calorimeter arrays.

In the Karlsruhe Tritium Neutrino Experiment, an international group of 200 researchers has joined forces to measure the mass of neutrinos. Neutrinos are the lightest, most common, but also the most puzzling particles in our universe. They are electrically neutral and interact with their environment only through gravity and the so-called weak nuclear force. This makes it difficult to measure their properties and the list of technical challenges to be solved is long.

Owing to its excellent source and spectrometer properties, the KATRIN experiment enables us to not only determine the neutrino mass, but also to search for a new variant of the particle: The right-handed partner of the neutrino, the so-called sterile neutrino. To find this particle, scientists are developing a novel detector called TRISTAN.

Neurodegenerative diseases like Alzheimer's are on the rise in the western world. Stem cell therapy can be significantly improved by a reversible local opening of the blood-brain barrier through focused ultrasound.

The aim of the ECHo experiment is to determine the neutrino mass in the sub-eV range by analysing the calorimetrically measured energy spectrum after the electron capture process of ¹⁶³Ho. A high-precision and high-statistical spectrum will be measured with the help of high-resolution superconducting sensors. Our contribution to this project is the development and manufacturing of the readout electronics for ECHo-100k.

To support the breast cancer diagnosis, suspicious structures that are only visible in the magnetic resonance tomogram of the breast are transferred to stereotactic X-ray mammograms. This should enable the more cost-effective and more widely available biopsy under X-ray control.

Within the HEIKA project, a model-based method for image registration of tomosynthesis and MRI data is being developed. The 3D imaging of the compressed breast in tomosynthesis allows for the first time a three-dimensional evaluation of complex biomechanical image registrations of breast images.

Advanced beam diagnostics detectors and technologies for future accelerators. Special emphasis is put on short-pulse physics and diagnostics. Our research benefits from the close collaboration of KIT accelerator and detector specialists. An example for the strength of this concept is the development of the novel beam diagnostics systems KAPTURE and KALYPSO.

Progress in recent years concerning X-ray optics, detector technology, and the tremendous increase of processing speed of commodity computational architectures gives rise to a paradigm shift in synchrotron X-ray imaging. UFO (Ultra-fast X-ray Imaging of Scientific Processes with On-line Assessment and Data-driven Process Control) aims to enable a new type of smart experiment using the vast computational power of massively parallel computation units: On-line assessment of sample dynamics will enable active image-based control, allow an unprecedented image quality, and will provide insight into so far inaccessible scientific processes.